The 8 Best Serums for Acne Prone Skin in 2025
I've been in the beauty industry for 4+ years now, although my background is originally in fine arts. In between researching and publishing our guides, I’m usually snacking and making spontaneous (and somewhat chaotic) choices about what to do with my hair.
Looking to venture into a new skin care serum but not sure what will help take control of acne and breakouts too?
Well, our Adore Beauty skincare experts have picked out our best serums to for acne-prone skin to help you get the beautiful and clear skin you all deserve.
Read on to find the best serum for acne prone skin for you—after all, acne shouldn't strictly define anyone’s skin.
Here Are the 8 Best Serums for Acne Prone Skin
Who says you have to spend a fortune to have beautiful skin? A favourite among trusted beauty bloggers and skincare gurus, The Ordinary Niacinamide 10% + Zinc 1%
is a high-performance acne serum that helps purify lacklustre, congested skin without breaking the bank. Naturally occurring Vitamin B3 eases inflammation while it balance sebum production. The result? This no-frills serum for acne prone skin helps you see fewer breakouts, smaller-looking pores, less redness, and a brighter complexion overall. Just remember that if you’re using a Vitamin C product, alternate the two, as Vitamin C and Niacinamide cancel each other out.
Sensitive skin types rejoice! There’s finally a retinoid for you.
The Ordinary Granactive Retinoid Emulsion 2% is a water-free serum for acne prone skin that offers all the anti-ageing and anti-acne benefits of Retinol, but without any irritation. This cruelty-free, gluten-free, vegan, lightweight solution is the perfect choice for fighting fine lines, wrinkles, and loss of firmness. Natural Tomato Extract and Jojoba Seed Oil help to balance oil production, making this night-time serum ideal for oily, acne-prone, and combination skin types. Plus, because this product is from The Ordinary, you get high performance without lowering your bank account.
Oil Free Serum for Acne Prone Skin
Why is the term ‘game changer’ frequently used to describe this product in online reviews? Quite frankly, because it’s so. This lightweight gel–cream feels cooling and soothing to the skin, and you can sense that it’s working right away. Zinc PCA helps reduce oiliness. Procerad minimises redness and swelling. Salicylic Acid helps unclog pores. And Mannose boosts skin-cell regeneration. Niacinamide is also in this serum for acne prone skin and works to balance sebum production and acne marks.
La Roche-Posay Effaclar Duo: Corrective and Unclogging Care zeroes in on stubborn spots and persistent flare-up areas to help improve texture and tone. Prevent new breakouts while correcting existing imperfections with this state-of-the-art serum.
Problematic skin? You’ll love this unique acne serum, which contains Açai, Copaiba Blossom, and other plant ingredients straight from the Amazon rainforest. If nothing has worked to keep your oilies away before, the Aspect Jungle Brew mattifying properties will immediately impress you. The ingredients in this chemical-free serum for acne prone skin minimise sebum production and promote balance, doing so without causing excess dryness. The redness and irritation commonly associated with acne are soothed, and skin feels comforted. Recommended for mild-to-moderate acne, this serum also boasts Stay-C 50, a highly effective form of Vitamin C, which helps eliminate the visible skin imperfections that often occur as a result of acne.
Natural Acne Control Serum for Blemish Prone Skin
Nourish and quench congested, thirsty skin with this protective skin serum. Pure, Australian Davidson Plum shields against harmful environmental aggressors. In fact, this ingredient packs a greater antioxidant punch than blueberries! We appreciate that this unique serum for acne prone skin contains just two ingredients yet is bursting with skin-pampering benefits. Not only does this natural acne serum work to eliminate blackheads and clogged pores, but it also helps to improve skin clarity and texture, giving you a radiant, lit-from-within look. This is the best day serum for acne prone skin.
If your skin has lost the lustre it once had, you can find that glow again thanks to asap radiance serum with aha/bha. Say goodbye to pimples and hello to radiance! This serum for acne prone skin is quite effective because it contains both alpha- and beta-hydroxy acids, which work together to conquer multiple skin issues. Various alpha-hydroxy acids exfoliate, encouraging cell turnover and removing flakes and dullness. Salicylic Acid, a beta-hydroxy acid, penetrates pores to lift away the debris that results in acne breakouts. Anti-ageing peptides round out this serum, helping boost collagen, giving skin a healthier, plumper appearance with fewer lines and wrinkles.
Best Serum for Acne and Wrinkles
It’s a common myth that acne breakouts only happen to teenagers. Hormonal fluctuations and chronological ageing create the perfect storm for producing adult acne. SkinCeuticals Blemish + Age Defense Serum addresses both issues head-on with this acne serum for ageing skin. Salicylic Acid works to lift bacteria from the pores, while Glycolic Acid exfoliates skin cells and helps to minimise the look of fine lines and wrinkles. Especially beneficial to those with breakouts, 2% Dioic Acid targets pigmentation, working to improve clarity and give skin back a more even tone. This high-performance formula is the perfect choice for those of you who want to tackle both the signs of ageing and the effects of acne.
Anti Ageing Serum for Acne Prone Skin
If you think you need to choose between anti-ageing and anti-acne, think again!
Skinstitut Retinol is a multitasking anti aging serum for acne prone skin that not only addresses your acne concerns but also does double duty as a potent weapon against the signs of skin ageing. This high-intensity gel–serum contains anti-ageing peptides and Retinol, a form of Vitamin A which promotes cell renewal and strengthens collagen and elastin fibers. A bonus? Skinstitut Retinol also helps regulate sebum production, making it an effective skin treatment option to minimise acne flare-ups and clogged pores. This luxe treatment will quickly become a favourite in your regimen. Use at night and make sure you are using SPF during the day.
Still on the search for the perfect serum? Try our serum and treatment quiz to find the best serums and treatments for acne-prone skin.
Brand and product inclusions are at the sole discretion of Adore Beauty. We do not seek or accept payment from brands or individuals listed in our guides.
Shop the 8 Best Serums for Acne Prone Skin Here:
SkinCeuticals Blemish + Age Defense Serum$145.00
asap radiance serum with aha/bha 30ml$97.50
Aspect Jungle Brew$130.00
The Ordinary Granactive Retinoid Emulsion 2% - 30ml$19.30
The Ordinary Niacinamide 10% + Zinc 1% - 30ml$9.50
Biologi Bd Luminosity Face Serum 30ml$55.00 $110.00 - Currently not available
La Roche-Posay Effaclar Duo + M$38.95
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